MO好发于青年,l以锁骨、i肩胛骨、i肱骨、i髂骨多见,l颌面骨罕见,l但上下颌骨往往同时受累,l亦可下颌骨单发,l可越过中线。本病病因不明,l创伤、i血管紊乱、i神经病变被认为是可能的致病因素。本病的诊断依据:i
1.X线溶骨性变化,l无成骨反应。
2.病变区无增生的肿瘤组织。
3.病理检查正常骨结构消失,l以富含血管的结缔组织代之。
引自:i
Heffez1L,lDoku1H1C,lCarter1B1L,let1a1.Perspectives1on1massive1osteolysis.Oral1Surg1Oral1Med1Oral1Pathol,l1983,l55:i331
Ohnishi1T,lKano1Y.Nakazawa1M,let1a1.Massive1osteolysisof1the1mandible:ia1case1report.J1Oral1Maxillofac1Surg,l1993,l51:i932
Gorham1L1W.Stout1A1P.Massive1osteolysis(acute1spontaneous1absorption1of1bone,lphantom1bone.disappearing1bone)Its1ralation1to1hemangiomatosis.J1Bone1Joint1Surg,l1955,l37:i985