皮肤肿瘤的分类(四)

WHO(1996)

1.黑色素细胞肿瘤11melanocytic1tumours

(1)良性(痣)11benign(naevi)

1)寻常后天性黑素细胞痣11common1acquired1melanocytic1naevi

①单纯性雀斑样痣11lentigo1simplex

②交界性黑色素细胞痣11junctional1melanocytic1naevus

③复合性黑色素细胞痣11compound1melanocytic1naevus

④真皮黑色素细胞痣11dermal1melanocytic1naevus

后天性痣的变异11variants1of1acquired1naevi

⑤晕痣11halo1naevus

⑥联合痣11combined1naevus

⑦深部穿透性痣111deep1penetrating1naevus

⑧复发性黑色素细胞痣111recurrent1melanocytic1naevus

2)梭形和上皮样细胞痣11spindle1and1epitheloid1cell1naevi

①spitz痣11spitz1naevus

②reed色素性梭形细胞痣111pigmented1spindle1cell1naevus1of1reed

3)蓝痣11blue1naevi

①寻常性蓝痣11common1blue1naevus

②细胞性蓝痣11cellular1blue1naevus

4)真皮黑色素细胞病11dermal1melanocytoses

①太田痣11naevus1of1ota

②伊藤痣11naevus1of1ito

③蒙古斑11mongolian1spot

5)先天性黑色素细胞痣11congenital1melanocytic1naevi

①小先天性痣11small1congenital1naevi

②中等大和巨形先天性痣11intermediate1and1giant1congenital1naevi

③先天性痣的增生性真皮损害11proliferative1dermal1lesions1in1congenital1naevi

6)发育不良性黑色素细胞痣11dysplastic1melanocytic1naevi

交界性和复合性发育不良痣11junctional1and1compound1dysplastic1naevi

(2)恶性(黑色素瘤及相关损害)11malignant(melanomas1and1related1lesions)

1)浅表扩展性黑色素瘤11superficial1spreading1melanoma

2)恶性雀斑样痣11lentigo1maligna

3)恶性雀斑样痣黑色素瘤11lentigo1maligna1melanoma

4)结节性黑色素瘤11nodular1melanoma

5)黑色素瘤伴未分类的表皮成分11melanoma1with1unclassified1epidermal1component

6)肢端-雀斑样痣黑色素瘤11acral-lentiginous1melanoma

7)黏膜-雀斑样痣黑色素瘤11mucosal-lentiginous1melanoma

8)促结缔组织增生性黑色素瘤11desmoplastic1melanoma

9)嗜神经性黑色素瘤11neurotropic1melanoma

10)恶性蓝痣11malignant1blue1naevus

①先天性黑素细胞痣黑色素瘤11melanoma1in1congenital1melanocytic1naevi

②轻度偏离型黑色素瘤11minimal1deviation1nelanoma

③透明细胞肉瘤11clear1cell1sarcoma

④恶性黑素细胞性雪旺细胞瘤11malignant1melanocytic1schwannoma

(3)非新生物性色素沉着11non-neoplastic1hyperpigmentations

1)雀斑11ephelis(freckle)

2)日光性(光化性)雀斑样痣11solar(actinic)lentigo

3)黏膜黑变病(生殖器雀斑样痣病)11mucosal1melanosis(genital1lentiginosis)

4)咖啡色斑11cafe1au1lait1spot

2.表皮肿瘤11epidermal1Tumours

(1)良性11benign

1)表皮11epidermal

①表皮痣11epidermal1naevus

②脂溢性角化病11seborrheic1keratosis

③透明细胞棘皮瘤11clear1cell1acanthoma

④纤维上皮性息肉(皮赘,l软瘊)11fibroepithelial1polyp(skin1tag,lacrodhordon)

⑤疣状角化不良瘤(孤立性毛囊角化不良病)11warty1dyskerastoma(isolated1dyskeratosis1follicularis)

⑥光化性角化病(日光性角化病)11actinic1keratosis(solar1keratosis)

⑦角棘皮瘤11keratoacanthoma

⑧良性苔藓样角化病(扁平苔藓样角化病)11benign1lichenoid1keratosis(lichen1planus-like1keratosis)

2)疣(病毒相关损害)11verrucae(virus-related1lesions)

①寻常疣11verruca1vulgaris(common1wart)

②跖疣11verruca1plantaris(plantar1wart)

③扁平疣11veruca1plana(flat1wart)

④尖锐湿疣11condyloma1acuminatum

⑤巨形尖锐湿疣(buschke1and1lowenstein)11giant1condyloma1accuminatum(buschke1and1lowenstein)

⑥鲍温病样丘疹病11bowenoid1papulosis

⑦传染性软疣11molluscum11contagiosum

(2)恶性11malignant

1)鳞状细胞癌变异11squamous1cell1carcinoma1variants

①梭形细胞鳞状细胞癌11spindle1cell1squamous1cell1carcinoma

②棘突松解性鳞状细胞癌11acantholytic1squamous1cell1carcinoma

③疣状鳞状细胞癌11verrucous1squamous1cell1carcinoma

④鳞状细胞癌伴皮角形成11squamous1cell1carcinoma1with1horn1formation

⑤淋巴上皮性鳞状细胞癌11lymphoepithelial1squamous1cell1carcinoma

2)基底细胞癌变异11basal1cell1carcinoma1variants

①多灶性浅表性基底细胞癌(浅表多中心性)11multifocal1superficial1basal1cell1carcinoma(superficial1multicentric)

②结节性基底细胞癌(实性、i腺样囊性)11nodular1basal1cell1carcinoma(solid,ladenoid1cystic)

③浸润性基底细胞癌11infiltrating1basal1cell1carcinoma

a.非硬化性11non-sclerosing

b.硬化性(促结缔组织增生性,l硬斑性)11sclerosing(desmoplastic,lmorpheic)

④纤维上皮性基底细胞癌11fibroepithelial1basal1cell1carcinoma

⑤基底细胞癌伴附属器分化11basal1cell1carcinoma1with1adnexal1differentiation

a.毛囊11follicular

b.小汗腺11eccrine

⑥基底鳞状细胞癌11basosquamous1carcinoma

⑦角化性基底细胞癌11keratotic1basal1cell1carcinoma

⑧色素性基底细胞癌11pigmented1basal1cell1carcinoma

⑨基底细胞痣综合征的基底细胞癌11basal1cell1carcinoma1in1basal1cell1naevus1syndrome

⑩微小结节性基底细胞癌11micronodular1basal1cell1carcinoma

3.附属器肿瘤11adnexal1tumours

(1)小汗腺肿瘤11eccrine1tumours

1)良性11benign

①纤毛性囊肿11ciliated1cyst

②汗腺囊瘤(小汗腺囊腺瘤)11hidrocystoma(eccrine1cystadenoma)

③乳头状小汗腺腺瘤11papillary1eccrine1adenoma

④汗管瘤11syringoma

⑤皮肤混合瘤(软骨样汗管瘤)11mixed1tumour1of1skin(chondroid1syringoma)

⑥小汗腺汗孔瘤11eccrine1poroma

⑦汗管纤维腺瘤11syringofibroadenoma

⑧结节状汗腺瘤(小汗腺末端螺旋瘤,l透明细胞汗腺瘤)11nodular1hidradenoma(eccrine1acrospiroma,lclear1cell1hidradenoma)

⑨小汗腺螺旋腺瘤11eccrine1spiradenoma

⑩圆柱瘤11cylindroma

2)恶性11malignant

①硬化性汗管癌(汗管瘤样癌,l微囊肿附属器癌)11sclerosing1sweat1duct1carcinoma(syringomatous1carcinoma,lmicrocystic1adnexal1carcinoma)

②皮肤恶性混合瘤(恶性软骨样汗管瘤)11malignant1mixed1tumour1of1the1skin(malignant1chondroid1syringoma)

③汗孔癌11porocarcinoma

④恶性结节状汗腺瘤11malignant1nodular1hidradenoma

⑤恶性小汗腺螺旋腺瘤11malignant1eccrine1spiradenoma

⑥黏液性小汗腺癌11mucilaginous1eccrine1carcinoma

⑦腺样囊性小汗腺癌11adenoid1cystic1eccrine1carcinoma

⑧侵袭性指(趾)乳头状腺瘤/腺癌11aggressive1digital1papillary1adenoma/adenocarcinoma

(2)大汗腺肿瘤11apocrine1tumours

1)良性11benign

①大汗腺囊腺瘤(汗腺囊瘤)11apocrine1cystad-enoma(hydrocystoma)

②乳头状汗腺瘤11hidradenoma1papilliferum

③乳头状汗管囊腺瘤11syringocystadenoma1papilliferum

④大汗腺腺瘤11apocrine1adenoma

⑤圆柱瘤11cylindroma

2)恶性11malignant

大汗腺腺癌11apocrine1adenocarcinoma

(3)皮脂腺肿瘤11sebaceous1gland1tumours

1)良性11benign

①皮脂腺腺瘤11sebaceous1adenoma

②皮脂腺上皮瘤11sebaceous1epithelioma

2)恶性11malignant

皮脂腺癌11sebaceous1carcinoma

3)毛皮脂腺增生及错构瘤11pilosebaceous1hyperplasia1and1hamartomas

①毛囊痣11follicular1naevi

②皮脂腺痣11naevus1sebaceous

③皮脂腺增生11sebaceous1gland1hyperplasia

(4)毛囊肿瘤11hair1follicle1tumours

1)良性11benign

①圆锥形毛囊漏斗棘皮瘤(扩张孔)11conical1infundibular1acanthoma(dilated1pore)

②毛鞘棘皮瘤11pilar1sheath1acanthoma

③外毛根鞘瘤11trichilemmoma

④毛囊漏斗肿瘤11tumour1of1follicular1infundibulum

⑤毛发上皮瘤11trichoepithelioma

⑥毛发毛囊瘤11trichofolliculoma

⑦毛母质瘤11pilomatricoma

⑧毛肿瘤(增生性外毛根鞘囊肿)11pilar1tumour(proliferating1trichilemmal1cyst)

2)恶性11malignant

①外毛根鞘癌11trichilemmocarcinoma

②恶性毛母质瘤(母质癌)11malignant1pilomatricoma1(matrical1carcinoma)

3)毛囊囊肿11follicular1cysts

①漏斗囊肿11infundibular1cyst

②外毛根鞘囊肿(毛囊肿)11trichilemmal1cyst(pilar1cyst)

③多发性皮脂囊瘤11steatocystoma1multiplex

④皮样囊肿11dermoid1cyst

⑤发疹性毳毛囊肿11eruptive1vellus1hair1cyst

4)毛皮脂间叶性肿瘤11tumours1of1pilosebaceous1mesenchyma

毛囊纤维瘤(毛盘瘤、i纤维毛囊瘤、i毛囊周围纤维瘤)11follicular1fibroma(trichodiscoma,lfibrofolliculoma,lperifollicular1fibroma)

4.派杰病11Paget1disease

(1)乳房派杰病11mammary1Paget1disease

(2)乳房外派杰病11extramammary1Paget1disease

5.皮肤淋巴增殖性肿瘤11cutaneous1lymphoproliferative1tumour

(1)皮肤T细胞淋巴瘤11cutaneous1T-cell1lymphoma

1)蕈样霉菌病11mycosis1fungoides

2)sezary综合征11sezary1syndrome

3)派杰样网状细胞增生病11(Woringer-Kol-lopp病)11pagetoid1reticulosis(Woringer-Kollop1disease)

4)成人T细胞淋巴瘤/白血病11adult1T-cell1iymphoma/leukemia

(2)皮肤B细胞淋巴瘤11cutaneous1B-cell1lymphoma

(3)皮肤浆细胞瘤11cutaneous1plasmacytoma

(4)皮肤淋巴瘤,l多形变异11cutaneous1lymphoma,lpleomorphic1variants

1)T淋巴母细胞淋巴瘤11T-immunoblastic1lymphoma

2)大细胞间变性淋巴瘤11large1cell1anaplastic1lymphoma

(5)发育不良性淋巴细胞增殖(淋巴瘤样血管炎)11dysplastic1lymphocytic1proliferations(lymphomatoid1vasculitis)

1)淋巴瘤样丘疹病11lymphomatoid1papulosis

2)淋巴瘤样肉芽肿病11lymphomatoid1granulomatosis

3)血管免疫母细胞性淋巴结病11angioimmunoblastic1lymphadenopathy

(6)朗格汉斯细胞组织细胞增生病(组织细胞增生病X)11langerhans1cell1histiocytosis(histiocytosis1X)

(7)退化性不典型组织细胞增生病11regressing1atypical1histiocytosis

(8)肥大细胞增生病11mastocytosis

(9)皮肤白血病11leukaemia1cutis

6.血管肿瘤11vascular1tumours

(1)良性11benign

1)毛细血管性血管瘤11capillary1haemangioma

2)海绵状血管瘤11cavernous1haemangioma

3)血管角化瘤11angiokeratoma

4)疣状角化性血管瘤11verrucous1keratotic1haemangioma

5)丛状血管瘤11tufted1haemangioma

6)梭形细胞血管内皮细胞瘤11spindle1cell1angioendothelioma

7)血状管球瘤11glomus1tumour

8)球血管瘤11glomangioma

(2)恶性11malignant

1)卡波西肉瘤11kaposi1sarcoma

2)1血管肉瘤11angiosarcoma

(3)血管畸形11vascular1malformations

1)鲜红斑痣11naevus1flammeus

2)遗传性出血性毛细血管扩张症11hereditory1haemorrhagic1telangiectasia

3)匍行性血管瘤11angioma1serpiginosum

(4)血管增生11vasoular1hyperplasias

1)肢端血管皮炎11acroangiodermatitis

2)血管内乳头状内皮细胞增生11intravascular1papillary1endothelial1hyperplasia

3)杆状血管瘤病11bacillary1angiomatosis

4)化脓性肉芽肿(分叶状血管瘤、i肉芽组织型血管瘤)11pyogenic1granuloma(lobular1haemangioma,lhaemangioma1of1granulation1tissue1type)

(5)血管淋巴样增生伴嗜酸粒细胞增多(上皮样血管瘤)11angiolymphoid1hyperplasia1with1eosinophilia(epitheloid1haemangioma)

7.淋巴管肿瘤11lymphatic1tumours

(1)良性11benign

1)毛细管性淋巴管瘤11capillary1lymphangioma

2)海绵状淋巴管瘤11cavernous1lymphangioma

3)囊状淋巴管瘤(湿瘤)11cystic1lymphangioma(hygroma)

(2)恶性11malignant

淋巴管肉瘤(恶性淋巴管内皮细胞瘤)11lymphangio1sarcoma(malignant1lymphangioendothelioma)

8.皮肤纤维组织细胞肿瘤11cutaneous1fibrohistiocytic1tumours

(1)良性11benign

1)良性纤维组织细胞瘤(皮肤纤维瘤、i组织细胞瘤、i硬化性血管瘤)变异11benign1fibrous1histiocytoma(dermatofibroma.histiocytoma,lsclerosing1haemangioma)variants

①细胞性良性纤维组织细胞瘤11cellular1benign1fibrous1histiocytoma

②动脉瘤性良性纤维组织细胞瘤11aneurysmal1bening1fibrous1histiocytoma

③上皮样良性纤维组织细胞瘤11epitheloid1benign1fibrous1histiocytoma

④非典型(假肉瘤性)良性纤维组织细胞瘤11atypical(pseudosarcomatous)benign1fibrous1histiocytoma

2)皮肤肌纤维瘤11dermatomyofibroma

3)良性(幼年性)黄色肉芽肿11benign(juvenile)xanthogranuloma

4)网状组织细胞瘤11reticulohistiocytoma

5)黄色瘤11xanthoma

(2)恶性11malignant

1)非典型性纤维黄色瘤11atypical1fibroxanthoma

2)皮肤隆突性纤维肉瘤11dermatofibrosarcoma1protuberans

3)恶性纤维组织细胞瘤11malignant1fibrous1histiocytoma

(3)血管纤维瘤性增生11angiofibromatous1proliferations

1)皮脂腺瘤11adenoma1sebaceum

2)纤维性丘疹11fibrous1papule

(4)指(趾)间叶性肿瘤11digital1mesenchymal1tumours

1)指(趾)纤维瘤11digital1fibroma

2)指(趾)纤维角化瘤11digital1fibrokeratoma

3)指(趾)黏液囊肿11digital1mucous1cyst

(5)婴幼儿真皮间叶性肿瘤11dermal1mesnchymal1tumours1of1infancy1and1childhood

1)婴儿肌纤维性瘤病11infantile1myofibromatosis

2)婴儿纤维错构瘤11fibrous1hamartoma1of1infancy

3)浅表性脂肪瘤样痣11naevus1lipomatosus1superficialis

4)幼年透明纤维瘤病11juvenile1hyaline1fibromatosis

5)巨细胞纤维母细胞瘤11giant1cell1fibroblastoma

(6)丛状纤维组织细胞性肿瘤11plexiform1fibrohistiocytic1tumours

9.神经组织肿瘤11nervous1tissue1tumours

(1)良性11benign

1)神经纤维瘤11neurofibroma

2)神经鞘瘤11neurilemoma

3)颗粒细胞瘤11granular1cell1tumour

4)皮肤神经鞘黏液瘤和神经鞘膜黏液瘤11dermal1nerve1sheath1myxoma1and1neurothekeoma

5)栅状包膜性神经瘤(孤立性神经瘤)11palisaded1encapsulated1neuroma(solitary1neuroma)

6)环层小体样神经纤维瘤(环层小体瘤)11pacinian1neurofibroma(pacinioma)

(2)恶性11malignant

1)恶性施万细胞瘤11malignant1schwannoma

2)恶性颗粒细胞瘤11malignant1granular1cell1tumour

10.肌肉肿瘤11tumours1of1muscle

(1)良性11benign

1)毛平滑肌瘤11piloleiomyomas

2)血管平滑肌瘤11angioleiomyoma

(2)恶性11malignant

浅表性平滑肌肉瘤11superficial1leiomyosarcoma

11.其他肿瘤11miscellneous1tumours

(1)原发性皮肤神经内分泌瘤(Merkel细胞癌)11primary1cutaneous1neuroendocrine1carcinoma(Merkel1cell1carcinoma)

(2)上皮样肉瘤11epitheloid1sarcoma